What antibiotics are used to treat prostatitis?

In some cases, antibiotics are included in the treatment regimen for prostatitis. The choice of a particular drug depends on a number of factors. Antibacterial therapy of acute and chronic forms of the disease has a number of significant differences.

Taking antibiotics is an important component of the successful treatment of acute and chronic prostatitis. The success of treatment largely depends on the correct selection of the drug and the scheme of its administration.

Indications for the appointment and the effect of antibiotics for prostatitis

Antibiotics are prescribed when it becomes obvious that the inflammation of the prostate is caused by an infection. This applies not only to the acute course of the disease, when pronounced symptoms are forced to provide emergency assistance. Chronic bacterial prostatitis, which occurs with a mild clinical picture or no symptoms at all, also needs antibiotic therapy.

The indication for taking antibiotics is not some specific symptom, but laboratory data indicating the presence of an infection.

To do this, use PCR (polymerase chain reaction method), which with high accuracy allows you to identify infections transmitted through sexual contact, as well as the study of urine and prostate secretion, which allows you to detect the presence of bacteria.

Sometimes infectious inflammation proceeds hidden - in this case, the level of leukocytes in the secretion of the gland does not exceed normal levels. To determine if there is an infection, the doctor prescribes a test dose of an antibiotic. After a week of taking this drug, the analysis is taken again, and if the level of leukocytes is above 25 units, we are talking about a hidden course of an infectious lesion of the prostate. In this case, antibiotics become mandatory.

The choice of antibiotic to treat inflammation of the prostate depends on several factors. The key is which bacteria have been identified and which drugs they are sensitive to. There is no universal cure.

The principle of action of antibiotics depends on what kind of medicine is used, the form of the disease and the causative agents of inflammation. However, the general essence can be reduced to several stages:

  1. The penetration of drugs into the blood by assimilation through the gastrointestinal tract or by intravenous administration.
  2. The penetration of active substances into the tissues of the prostate gland and the destruction of the causative agent of the disease.
  3. The effect of accumulation in the tissues of the gland, which allows you to fight infection on an ongoing basis.

The last step is particularly important, as some antibiotics are only bacteriostatic. This means that they only affect dividing cells. At the same time, those cells that are in an anaerobic state remain unnoticed by them. If the active substance of the drug does not accumulate in the tissues of the prostate, then the bacteria that have left the anaerobic state will quickly negate the entire effect of the treatment.

There are bacteria that are highly resistant to drugs. These are perhaps the most common causative agents of prostatitis, for example, Escherichia coli. They build hard capsules and biofilms that reduce the effects of active drug ingredients. In this case, it is necessary that the drugs have the ability to destroy the protective shells of these bacteria. It is also important to take the drugs to the end, even when the symptoms of the disease have already disappeared.

Groups of antibacterial agents for the treatment of prostatitis

There are several groups of antibiotics that are effective (singly or in combination) against bacteria that cause inflammation of the prostate gland. The choice of a specific group of drugs depends on a number of factors: "weak spots" in the identified bacteria, the patient's comorbidities, the severity of the course of prostatitis, its form and side effects of the drug.

The main groups of antibacterial drugs for prostatitis include:

  • tetracyclines;
  • penicillins;
  • cephalosporins;
  • macrolides;
  • fluoroquinolones.

Tetracycline series

Antibiotics of this group have a bacteriostatic effect, which means that they prevent cell division, growth and development.

Do not think that bacteriostatic drugs are unambiguously ineffective. This effect is sufficient to eliminate the infection, provided that the patient does not have impaired immunity.

Such drugs disrupt the connection between RNA (which "gives commands" for the development and division of pathogens) and the ribosome (which carries out these "commands"), thus suppressing the production of protein - the building material for new cells.

man taking antibiotic for prostatitis

The drugs of this group are effective in the fight against the following pathogens:

  • mycoplasmas;
  • ureaplasma;
  • chlamydia;
  • enterococci;
  • enterobacteria;
  • klebsiella;
  • pseudomonas;
  • seration;
  • coli.

Drugs in this group are prescribed selectively because of the large list of side effects.

Penicillin series

Preparations of this group also have a bacteriostatic effect, affecting dividing bacteria. However, they have a different principle of action: they stop the production of the main component of the bacterial cell wall - peptidoglycan.

Since there are many bacteria that have developed resistance to antibiotics in this group, a subgroup of protected penicillins has been developed.

These antibiotics are effective in treating inflammation caused by the following bacteria:

  • gonococci;
  • staphylococci;
  • enterobacteria;
  • Proteus;
  • klebsiella;
  • seration;
  • coli.

Drugs in this group are prescribed carefully due to the high risk of allergic reactions. To treat inflammation of the prostate, drugs based on oxacillin, ampicillin and amoxicillin are prescribed.


These are powerful bactericidal drugs that not only prevent cell division, but destroy them. This occurs in two steps: disruption of peptidoglycan production (destruction of the cell wall) and release of enzymes.

Medicines of this group are effective against:

  • gonococci;
  • enterobacteria;
  • Proteus bacteria;
  • Klebsiella;
  • coli.

The drugs in this group include drugs based on ceftriaxone, cefilin, cefpiron and others.


The group of the safest antibiotics that cause the least side effects. The principle of their action is the cessation of protein production for cell construction. What will be the effect (bactericidal or bacteriostatic) depends on the choice of the drug and its concentration in the body.

a man is studying an annotation for an antibiotic for prostatitis

Antibiotics from this group are effective against the following bacteria:

  • gonococci;
  • chlamydia;
  • ureaplasma;
  • mycoplasmas.

Not all doctors prescribe drugs in this group for the treatment of prostatitis, since, although their effect is logical to assume, narrow studies have not been conducted on this subject. The drugs in this group include drugs based on azithromycin and clarithromycin.


These are not antibiotics in their classical sense, because antibiotics are drugs of natural origin or their closest synthetic counterparts. Fluoroquinolones have no analogues in nature.

The drugs of this particular group are most often prescribed by urologists. And there are good reasons for this:

  • Firstly, they have a very wide spectrum of bactericidal action, not inferior to natural antibiotics with fewer side effects.
  • Secondly, they have a very active antimicrobial effect: they affect both the production of DNA, preventing its copying, and topoisomerase (an important part of the integration of the virus into cells), and RNA, and the walls of cell membranes and other processes that ensure vital activity andthe process of cell division - such a massive attack from all fronts has good results.

Fluoroquinolones are effective against:

  • intestinal and Pseudomonas aeruginosa;
  • staphylococci;
  • gonococci;
  • mycoplasmas;
  • chlamydia and other bacteria.

Antibiotics of this group are used for the complex treatment of Koch's bacillus. Therefore, before you start taking these drugs, it is important to make sure that there are no causative agents of tuberculosis in the body. The fact is that a separate intake of fluoroquinolones helps Koch's sticks to develop resistance to other antibiotics, and the process of treating tuberculosis becomes much more complicated.

The most effective antibiotics for inflammation of the prostate

Even the most effective antibiotic will be useless and even harmful if the reason for choosing this drug is advertising, the opinion of incompetent people who have been helped by this remedy, or the fact that this drug was effective last time. There is no drug that is active against all bacteria and viruses, but each group of antibiotics has its best representatives.

General principles and features of antibiotic therapy for acute and chronic prostatitis

The treatment regimen and the choice of drugs depends on the form of prostatitis. There are both similarities and differences in the treatment of acute and chronic prostatitis.

For treatment with antibiotic therapy of any type of prostatitis, the following aspects are characteristic:

  • contacting a doctor and passing tests to identify the pathogen is mandatory;
  • treatment should be continued according to the scheme, even when it seems that a complete recovery has come.

At the same time, when choosing drugs for the treatment of inflammation, you need to take into account some different factors. So, for the treatment of chronic prostatitis, the ability of active substances to penetrate into prostate cells is of fundamental importance. It has been proven that just a high concentration of the drug in the blood is not enough. Not all broad-spectrum drugs, even of the latest generations, have such abilities. The situation is different when it comes to acute inflammation: it increases the permeability of prostate cells for the entry of drugs from the blood.

The ability of drugs to penetrate and accumulate in tissues is of fundamental importance in chronic inflammation, but not so important in acute inflammation.

The second difference is that the acute phase should be treated as quickly as possible, given the severity of the condition. Therefore, preference is given to bactericidal drugs (fluoroquinolones), rather than bacteriostatic ones. In cases where the principle of action of the drug depends on the dosage, the concentration of the drug in the blood and prostate should be sufficient to maintain the bactericidal effect - this applies to drugs from the macrolide group.

Bacteriostatic antibiotics are selected for the treatment of chronic inflammation, and bactericidal antibiotics for acute inflammation.

Natural antibiotics: effectiveness and methods of application

Considering that almost all antibiotics are of natural origin (or are the closest analogues), it is logical to assume that herbs have a similar effect with better tolerance and fewer side effects.

However, if the action of herbs were sufficient, there would be no need for the production of medicines. Therefore, herbal therapy with antibacterial properties is only suitable as an adjuvant treatment or preventive measure for chronic inflammation of the prostate gland.

There are several herbs that can fight bacteria:

  • yarrow (can have both bactericidal and bacteriostatic effect on E. coli and enterobacteria);
  • bitter wormwood (effective against Escherichia and Pseudomonas aeruginosa);
  • eleutherococcus (fights white staphylococcus aureus, E. coli and enterobacteria);
  • plantain large (fights white staphylococcus, enterobacteria, has a bacteriostatic effect on proteus, has an analgesic effect).

There are many recipes that can be used to prepare an antibacterial drug to relieve inflammation. From herbs it is better to prepare infusions that do not need prolonged exposure to temperature.

herbal decoction as a natural antibiotic for prostatitis

For almost any herb, the following recipe is suitable:

  1. To one part of the herb, take ten parts of water at room temperature.
  2. Heat the mixture for a quarter of an hour in a boiling water bath.
  3. Infuse for 45 minutes.
  4. Pass through a filter, such as gauze.

Infusions are most effective if taken immediately after preparation.

In addition, to combat prostatitis, hazel bark, aspen and chestnut peel are used. From such material it is better to prepare decoctions. Each plant has its own recipe, but in general terms, the preparation of a decoction is as follows:

  1. Wash and grind raw materials.
  2. Put in water so that it completely covers the branches or bark.
  3. Boil in a water bath for half an hour.
  4. Let cool for 10 minutes and drain the broth, squeezing the raw material.

Broths can be taken within 2 days from the moment of preparation.

The effectiveness of treatment depends on several factors: the choice of the desired natural antibiotic, the acquisition of high-quality raw materials (it is better to prepare it yourself) and the correct preparation of the infusion or decoction.

Antibiotics for prostatitis are selected depending on the infection that caused the inflammation, the form of the disease and the general health of the patient. Each medicine has contraindications and side effects, so you should consult a urologist before taking it. The same applies to medicinal herbs with an antibacterial effect.